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SARS-CoV-2 suppresses IFNß production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.
Shemesh, Maya; Aktepe, Turgut E; Deerain, Joshua M; McAuley, Julie L; Audsley, Michelle D; David, Cassandra T; Purcell, Damian F J; Urin, Victoria; Hartmann, Rune; Moseley, Gregory W; Mackenzie, Jason M; Schreiber, Gideon; Harari, Daniel.
Afiliação
  • Shemesh M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Aktepe TE; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Melbourne, Victoria, Australia.
  • Deerain JM; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Melbourne, Victoria, Australia.
  • McAuley JL; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Melbourne, Victoria, Australia.
  • Audsley MD; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Victoria, Australia.
  • David CT; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Victoria, Australia.
  • Purcell DFJ; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Melbourne, Victoria, Australia.
  • Urin V; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Hartmann R; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
  • Moseley GW; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Victoria, Australia.
  • Mackenzie JM; Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Parkville, Melbourne, Victoria, Australia.
  • Schreiber G; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
  • Harari D; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
PLoS Pathog ; 17(8): e1009800, 2021 08.
Article em En | MEDLINE | ID: mdl-34437657

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Interferon beta / SARS-CoV-2 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Interferon beta / SARS-CoV-2 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article