Single Dose of N-Acetylcysteine in Local Anesthesia Increases Expression of HIF1&#945;, MAPK1, TGFß1 and Growth Factors in Rat Wound Healing.

Paskal, Wiktor; Kopka, Michal; Stachura, Albert; Paskal, Adriana M; Pietruski, Piotr; Pelka, Kacper; Woessner, Alan E; Quinn, Kyle P; Galus, Ryszard; Wejman, Jaroslaw; Wlodarski, Pawel

Single Dose of N-Acetylcysteine in Local Anesthesia Increases Expression of HIF1α, MAPK1, TGFß1 and Growth Factors in Rat Wound Healing.

Paskal, Wiktor; Kopka, Michal; Stachura, Albert; Paskal, Adriana M; Pietruski, Piotr; Pelka, Kacper; Woessner, Alan E; Quinn, Kyle P; Galus, Ryszard; Wejman, Jaroslaw; Wlodarski, Pawel.

Afiliação

Paskal W; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Kopka M; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Stachura A; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Paskal AM; Doctoral School, Medical University of Warsaw, 02-091 Warsaw, Poland.
Pietruski P; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Pelka K; Centre of Postgraduate Medical Education, Department of Replantation and Reconstructive Surgery, Gruca Teaching Hospital, 05-400 Otwock, Poland.
Woessner AE; Department of Methodology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Quinn KP; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Galus R; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Wejman J; Department of Histology and Embryology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Wlodarski P; Department of Pathology, Centre of Postgraduate Medical Education, 00-416 Warsaw, Poland.

Int J Mol Sci ; 22(16)2021 Aug 12.

Article em En | MEDLINE | ID: mdl-34445365

Assuntos

Acetilcisteína/administração & dosagem; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Proteína Quinase 1 Ativada por Mitógeno/genética; Fator de Crescimento Transformador beta1/genética; Cicatrização/efeitos dos fármacos; Acetilcisteína/farmacologia; Anestesia Local; Animais; Antígenos CD/metabolismo; Antígenos de Diferenciação Mielomonocítica/metabolismo; Modelos Animais de Doenças; Regulação da Expressão Gênica/efeitos dos fármacos; Estresse Oxidativo/efeitos dos fármacos; Peroxidase/metabolismo; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Ratos; Ratos Sprague-Dawley

Palavras-chave

N-Acetylcysteine; growth factor; incision; local anesthesia additive; qPCR; rat; regeneration; skin; therapy; wound healing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilcisteína / Cicatrização / Proteína Quinase 1 Ativada por Mitógeno / Subunidade alfa do Fator 1 Induzível por Hipóxia / Fator de Crescimento Transformador beta1 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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