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A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD-Pass.
Hölper, Julia E; Grey, Finn; Baillie, John Kenneth; Regan, Tim; Parkinson, Nicholas J; Höper, Dirk; Thamamongood, Thiprampai; Schwemmle, Martin; Pannhorst, Katrin; Wendt, Lisa; Mettenleiter, Thomas C; Klupp, Barbara G.
Afiliação
  • Hölper JE; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
  • Grey F; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
  • Baillie JK; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
  • Regan T; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh EH25 9RG, UK.
  • Parkinson NJ; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
  • Höper D; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
  • Thamamongood T; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
  • Schwemmle M; Institute of Virology, Medical Center-University of Freiburg, 79110 Freiburg, Germany.
  • Pannhorst K; Spemann Graduate School of Biology and Medicine, University of Freiburg, 79110 Freiburg, Germany.
  • Wendt L; Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.
  • Mettenleiter TC; Institute of Virology, Medical Center-University of Freiburg, 79110 Freiburg, Germany.
  • Klupp BG; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Viruses ; 13(8)2021 08 09.
Article em En | MEDLINE | ID: mdl-34452438
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Viral / Transferases (Outros Grupos de Fosfato Substituídos) / Herpesvirus Suídeo 1 / Sistemas CRISPR-Cas / Interações entre Hospedeiro e Microrganismos / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Viral / Transferases (Outros Grupos de Fosfato Substituídos) / Herpesvirus Suídeo 1 / Sistemas CRISPR-Cas / Interações entre Hospedeiro e Microrganismos / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article