Activity-dependent release of phosphorylated human tau from Drosophila neurons in primary culture.

Ismael, Sazan; Sindi, Ghadir; Colvin, Robert A; Lee, Daewoo

Ismael, Sazan; Sindi, Ghadir; Colvin, Robert A; Lee, Daewoo.

Afiliação

Ismael S; Neuroscience Program, Department of Biological Sciences, and Molecular and Cellular Biology Interdisciplinary Graduate Program, Ohio University, Athens, Ohio, USA.
Sindi G; Neuroscience Program, Department of Biological Sciences, and Molecular and Cellular Biology Interdisciplinary Graduate Program, Ohio University, Athens, Ohio, USA.
Colvin RA; Neuroscience Program, Department of Biological Sciences, and Molecular and Cellular Biology Interdisciplinary Graduate Program, Ohio University, Athens, Ohio, USA.
Lee D; Neuroscience Program, Department of Biological Sciences, and Molecular and Cellular Biology Interdisciplinary Graduate Program, Ohio University, Athens, Ohio, USA. Electronic address: leed1@ohio.edu.

J Biol Chem ; 297(4): 101108, 2021 10.

Article em En | MEDLINE | ID: mdl-34473990

Assuntos

Doença de Alzheimer/metabolismo; Mutação de Sentido Incorreto; Neurônios/metabolismo; Proteínas tau/metabolismo; Doença de Alzheimer/genética; Substituição de Aminoácidos; Animais; Células Cultivadas; Drosophila melanogaster; Humanos; Luz; Fosforilação; Proteínas tau/genética

Palavras-chave

Drosophila; activity-dependent release; human tau release; phosphorylation; primary neuronal culture

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas tau / Mutação de Sentido Incorreto / Doença de Alzheimer / Neurônios Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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