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Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis.
Fisher, Allison L; Srole, Daniel N; Palaskas, Nicolaos J; Meriwether, David; Reddy, Srinivasa T; Ganz, Tomas; Nemeth, Elizabeta.
Afiliação
  • Fisher AL; Molecular, Cellular and Integrative Physiology Graduate Program, Graduate Programs in Bioscience, UCLA, Los Angeles, California, USA; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Srole DN; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA; Molecular and Medical Pharmacology Graduate Program, Graduate Programs in Bioscience, UCLA, Los Angeles, California, USA.
  • Palaskas NJ; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Meriwether D; Division of Cardiology, Department of Medicine, UCLA, Los Angeles, California, USA.
  • Reddy ST; Division of Cardiology, Department of Medicine, UCLA, Los Angeles, California, USA.
  • Ganz T; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
  • Nemeth E; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA. Electronic address: ENemeth@mednet.ucla.edu.
J Biol Chem ; 297(4): 101156, 2021 10.
Article em En | MEDLINE | ID: mdl-34480898
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Férricos / Colesterol / Fator de Necrose Tumoral alfa / Apoptose / Células Endoteliais da Veia Umbilical Humana / Compostos de Amônio Quaternário / Ferro Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Férricos / Colesterol / Fator de Necrose Tumoral alfa / Apoptose / Células Endoteliais da Veia Umbilical Humana / Compostos de Amônio Quaternário / Ferro Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article