S<sub>16</sub> and T<sub>18</sub> mannosylation sites of LppX are not essential for its activity in phthiocerol dimycocerosates localization at the surface of Mycobacterium tuberculosis.

Labarre, Cécile; Dautin, Nathalie; Grzegorzewicz, Anna; Jackson, Mary; McNeil, Michael; Mohiman, Niloofar; Sago, Laila; Bayan, Nicolas

S₁₆ and T₁₈ mannosylation sites of LppX are not essential for its activity in phthiocerol dimycocerosates localization at the surface of Mycobacterium tuberculosis.

Labarre, Cécile; Dautin, Nathalie; Grzegorzewicz, Anna; Jackson, Mary; McNeil, Michael; Mohiman, Niloofar; Sago, Laila; Bayan, Nicolas.

Afiliação

Labarre C; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France. Electronic address: cecile.labarre@i2bc.paris-saclay.fr.
Dautin N; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France; Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, Université de Paris, LBPC-PM, CNRS, UMR7099, 75005, Paris, France. Electronic address:
Grzegorzewicz A; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Colorado, Fort Collins, USA. Electronic address: Anna.Grezegorzewic@colostate.edu.
Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Colorado, Fort Collins, USA. Electronic address: Mary.Jackson@colostate.edu.
McNeil M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Colorado, Fort Collins, USA. Electronic address: M.Mcneil@colostate.edu.
Mohiman N; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France; Innovagen AB, Ideon Science Park, SE-22370, Lund, Sweden. Electronic address: nm@innovagen.com.
Sago L; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France. Electronic address: laila.sago@i2bc.paris-saclay.fr.
Bayan N; Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France. Electronic address: nicolas.bayan@i2bc.paris-saclay.fr.

Res Microbiol ; 172(7-8): 103874, 2021.

Article em En | MEDLINE | ID: mdl-34492336

Assuntos

Proteínas de Bactérias/metabolismo; Lipídeos/análise; Lipoproteínas/metabolismo; Mycobacterium tuberculosis/metabolismo; Fatores de Virulência/metabolismo; Proteínas de Bactérias/química; Proteínas de Bactérias/genética; Membrana Celular/metabolismo; Corynebacterium glutamicum/genética; Corynebacterium glutamicum/metabolismo; Glicosilação; Metabolismo dos Lipídeos; Lipoproteínas/química; Lipoproteínas/genética; Manosiltransferases/genética; Manosiltransferases/metabolismo; Mutagênese Sítio-Dirigida; Mycobacterium smegmatis/genética; Mycobacterium smegmatis/metabolismo; Mycobacterium tuberculosis/patogenicidade; Virulência; Fatores de Virulência/química; Fatores de Virulência/genética

Palavras-chave

Corynebacterium glutamicum; Glycosylation; Mycobacterium; Phthiocerol dimycocerosates

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Fatores de Virulência / Lipídeos / Lipoproteínas / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google