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A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors.
Di Giulio, Stefano; Colicchia, Valeria; Pastorino, Fabio; Pedretti, Flaminia; Fabretti, Francesca; Nicolis di Robilant, Vittoria; Ramponi, Valentina; Scafetta, Giorgia; Moretti, Marta; Licursi, Valerio; Belardinilli, Francesca; Peruzzi, Giovanna; Infante, Paola; Goffredo, Bianca Maria; Coppa, Anna; Canettieri, Gianluca; Bartolazzi, Armando; Ponzoni, Mirco; Giannini, Giuseppe; Petroni, Marialaura.
Afiliação
  • Di Giulio S; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Colicchia V; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Pastorino F; Department of Biology, University Tor Vergata, 00173, Rome, Italy.
  • Pedretti F; Laboratory of Experimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, 16147, Genoa, Italy.
  • Fabretti F; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Nicolis di Robilant V; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
  • Ramponi V; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Scafetta G; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Moretti M; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Licursi V; Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), 08028, Barcelona, Spain.
  • Belardinilli F; Pathology Research Laboratory, Sant'Andrea University Hospital, 00189, Rome, Italy.
  • Peruzzi G; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Infante P; Department of Biology and Biotechnologies "Charles Darwin", University La Sapienza, 00185, Rome, Italy.
  • Goffredo BM; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Coppa A; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy.
  • Canettieri G; Center for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy.
  • Bartolazzi A; Metabolic Pathology Lab, Ospedale Pediatrico Bambino Gesù, 00165, Roma, Italy.
  • Ponzoni M; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Giannini G; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Petroni M; Istituto Pasteur-Fondazione Cenci Bolognetti, 00161, Rome, Italy.
Oncogene ; 40(43): 6143-6152, 2021 10.
Article em En | MEDLINE | ID: mdl-34508175
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Pirazóis / Pirimidinas / Neoplasias Cerebelares / Proteína Proto-Oncogênica N-Myc / Meduloblastoma / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Pirazóis / Pirimidinas / Neoplasias Cerebelares / Proteína Proto-Oncogênica N-Myc / Meduloblastoma / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article