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Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression.
Bakhoum, Mathieu F; Francis, Jasmine H; Agustinus, Albert; Earlie, Ethan M; Di Bona, Melody; Abramson, David H; Duran, Mercedes; Masilionis, Ignas; Molina, Elsa; Shoushtari, Alexander N; Goldbaum, Michael H; Mischel, Paul S; Bakhoum, Samuel F; Laughney, Ashley M.
Afiliação
  • Bakhoum MF; Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA. mathieu.bakhoum@gmail.com.
  • Francis JH; Department of Ophthalmology, University of California San Diego, La Jolla, CA, USA. mathieu.bakhoum@gmail.com.
  • Agustinus A; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Earlie EM; Department of Ophthalmology, Weill Cornell Medical School, New York, NY, USA.
  • Di Bona M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Abramson DH; Department of Pharmacology, Weill Cornell Graduate School, New York, NY, USA.
  • Duran M; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
  • Masilionis I; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Molina E; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Shoushtari AN; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Goldbaum MH; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mischel PS; Department of Ophthalmology, Weill Cornell Medical School, New York, NY, USA.
  • Bakhoum SF; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Laughney AM; The Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Commun ; 12(1): 5402, 2021 09 13.
Article em En | MEDLINE | ID: mdl-34518527
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Regulação Neoplásica da Expressão Gênica / Perfilação da Expressão Gênica / Instabilidade Cromossômica / Complexo Repressor Polycomb 1 / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Regulação Neoplásica da Expressão Gênica / Perfilação da Expressão Gênica / Instabilidade Cromossômica / Complexo Repressor Polycomb 1 / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article