TRAPPC4 regulates the intracellular trafficking of PD-L1 and antitumor immunity.

Ren, Yimeng; Qian, Yun; Ai, Luoyan; Xie, Yile; Gao, Yaqi; Zhuang, Ziyan; Chen, Jinxian; Chen, Ying-Xuan; Fang, Jing-Yuan

Ren, Yimeng; Qian, Yun; Ai, Luoyan; Xie, Yile; Gao, Yaqi; Zhuang, Ziyan; Chen, Jinxian; Chen, Ying-Xuan; Fang, Jing-Yuan.

Afiliação

Ren Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Qian Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ai L; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Xie Y; Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Gao Y; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhuang Z; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen J; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen YX; Division of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Fang JY; State Key Laboratory for Oncogenes and Related Genes; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Nat Commun ; 12(1): 5405, 2021 09 13.

Article em En | MEDLINE | ID: mdl-34518538

Assuntos

Antígeno B7-H1/imunologia; Neoplasias Colorretais/imunologia; Regulação Neoplásica da Expressão Gênica/imunologia; Proteínas do Tecido Nervoso/imunologia; Proteínas de Transporte Vesicular/imunologia; Animais; Antígeno B7-H1/genética; Antígeno B7-H1/metabolismo; Linhagem Celular Tumoral; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Citotoxicidade Imunológica/genética; Citotoxicidade Imunológica/imunologia; Endossomos/imunologia; Endossomos/metabolismo; Células HCT116; Humanos; Espaço Intracelular/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Knockout; Proteínas do Tecido Nervoso/genética; Proteínas do Tecido Nervoso/metabolismo; Receptor de Morte Celular Programada 1/genética; Receptor de Morte Celular Programada 1/imunologia; Receptor de Morte Celular Programada 1/metabolismo; Ligação Proteica; Transporte Proteico; Interferência de RNA; Linfócitos T/imunologia; Linfócitos T/metabolismo; Proteínas de Transporte Vesicular/genética; Proteínas de Transporte Vesicular/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Regulação Neoplásica da Expressão Gênica / Proteínas de Transporte Vesicular / Antígeno B7-H1 / Proteínas do Tecido Nervoso Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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