Long-Term Outcomes of the Mosaic Mitral Porcine Bioprosthesis in Japanã- Results From the Japan Mosaic Valve Long-Term Multicenter Study.
Circ J
; 86(3): 449-457, 2022 02 25.
Article
em En
| MEDLINE
| ID: mdl-34526438
ABSTRACT
BACKGROUND:
This study retrospectively evaluated the long-term patient outcomes and durability of the Mosaic mitral porcine bioprosthesis in the Japan Mosaic valve long-term multicenter study.MethodsâandâResults:
The medical records of 390 patients who underwent mitral valve replacement with the Mosaic bioprosthesis at 10 centers in Japan (1999-2014) were reviewed. Patient data were collected using the Research Electronic Data Capture software. Patient survival was determined using the Kaplan-Meier method. Freedom from structural valve deterioration (SVD) and valve-related reoperation and death were determined using actuarial methods. The median (interquartile range [IQR]) age of the cohort was 73 (69-77) years. The median (IQR) follow-up period was 4.83 (1.84-8.26) years. The longest follow-up period was 15.8 years. The 30-day mortality rate was 5.4%. The 12-year actuarial survival rate was 54.1±4.5%, and the freedom from valve-related death was 85.3±3.4%. The freedom from reoperation at 12 years was 74.3±5.7%. The freedom from SVD at 12 years was 81.4±6.6% for patients aged ≥65 years and 71.6±11.1% for those aged <65 years. The median (IQR) mean pressure gradient was 4.1 (3.0-6.0) and 5.6 (4.0-6.7) mmHg at 1 and 10 years, respectively. The median (IQR) effective orifice area was 1.7 (1.4-2.0) and 1.4 (1.2-1.6) cm2at 1 and 10 years, respectively.CONCLUSIONS:
The Mosaic porcine bioprosthesis offered satisfactory long-term outcomes for up to 12 years.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bioprótese
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Próteses Valvulares Cardíacas
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Implante de Prótese de Valva Cardíaca
Tipo de estudo:
Observational_studies
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Prognostic_studies
Limite:
Animals
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Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article