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Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.
Yang, Chunfu; Lei, Lei; Collins, John W Marshall; Briones, Michael; Ma, Li; Sturdevant, Gail L; Su, Hua; Kashyap, Anuj K; Dorward, David; Bock, Kevin W; Moore, Ian N; Bonner, Christine; Chen, Chih-Yu; Martens, Craig A; Ricklefs, Stacy; Yamamoto, Masahiro; Takeda, Kiyoshi; Iwakura, Yoichiro; McClarty, Grant; Caldwell, Harlan D.
Afiliação
  • Yang C; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Lei L; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Collins JWM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Briones M; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Ma L; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Sturdevant GL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
  • Su H; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Kashyap AK; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Dorward D; Research Technology Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
  • Bock KW; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Bonner C; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
  • Chen CY; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
  • Martens CA; Genomics Unit, Research Technology Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
  • Ricklefs S; Genomics Unit, Research Technology Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
  • Yamamoto M; Department of Immunoparasitology, Research Institute for Microbial Diseases (RIMD), Osaka University, Osaka, Japan.
  • Takeda K; Laboratory of Mucosal Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
  • Iwakura Y; Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, Japan.
  • McClarty G; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.
  • Caldwell HD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. hcaldwell@niaid.nih.gov.
Nat Commun ; 12(1): 5454, 2021 09 15.
Article em En | MEDLINE | ID: mdl-34526512
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Chlamydia / Chlamydia / Células Mieloides / Receptores Purinérgicos P2X7 / Proteína 3 que Contém Domínio de Pirina da Família NLR / Inflamação / Neutrófilos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Chlamydia / Chlamydia / Células Mieloides / Receptores Purinérgicos P2X7 / Proteína 3 que Contém Domínio de Pirina da Família NLR / Inflamação / Neutrófilos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article