HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-&#954;B Signaling Pathway in Macrophages.

Song, Xiaotian; Gao, Xue; Wang, Yadong; Raja, Rameez; Zhang, Yaoyu; Yang, Shulin; Li, Miao; Yao, Zhiyan; Wei, Lin

HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages.

Song, Xiaotian; Gao, Xue; Wang, Yadong; Raja, Rameez; Zhang, Yaoyu; Yang, Shulin; Li, Miao; Yao, Zhiyan; Wei, Lin.

Afiliação

Song X; Department of Immunology, Hebei Medical University, Shijiazhuang, China.
Gao X; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Wang Y; Department of Immunology, Hebei Medical University, Shijiazhuang, China.
Raja R; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Zhang Y; Department of Infectious Diseases, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yang S; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.
Li M; Department of Immunology, Hebei Medical University, Shijiazhuang, China.
Yao Z; Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, China.
Wei L; Department of Immunology, Hebei Medical University, Shijiazhuang, China.

Front Immunol ; 12: 654998, 2021.

Article em En | MEDLINE | ID: mdl-34531848

Assuntos

Quimiocina CCL2/imunologia; Quimiocina CXCL10/imunologia; Hepacivirus/imunologia; Macrófagos/imunologia; NF-kappa B/imunologia; Transdução de Sinais/imunologia; Proteínas do Core Viral/imunologia; Animais; Células Cultivadas; Quimiocina CCL2/genética; Quimiocina CCL2/metabolismo; Quimiocina CXCL10/genética; Quimiocina CXCL10/metabolismo; Expressão Gênica/imunologia; Hepacivirus/metabolismo; Hepacivirus/fisiologia; Hepatite C/imunologia; Hepatite C/metabolismo; Hepatite C/virologia; Interações Hospedeiro-Patógeno/imunologia; Humanos; Células de Kupffer/imunologia; Células de Kupffer/metabolismo; Células de Kupffer/virologia; Macrófagos/metabolismo; Macrófagos/virologia; Camundongos; Camundongos Endogâmicos BALB C; Células RAW 264.7; Células THP-1; Proteínas do Core Viral/metabolismo

Palavras-chave

CCL2; CXCL10; HCV core protein; chemokines; macrophages

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas do Core Viral / NF-kappa B / Hepacivirus / Quimiocina CCL2 / Quimiocina CXCL10 / Macrófagos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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