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RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.
Bekele, Raie T; Samant, Amruta S; Nassar, Amin H; So, Jonathan; Garcia, Elizabeth P; Curran, Catherine R; Hwang, Justin H; Mayhew, David L; Nag, Anwesha; Thorner, Aaron R; Börcsök, Judit; Sztupinszki, Zsofia; Pan, Chong-Xian; Bellmunt, Joaquim; Kwiatkowski, David J; Sonpavde, Guru P; Van Allen, Eliezer M; Mouw, Kent W.
Afiliação
  • Bekele RT; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Samant AS; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Nassar AH; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • So J; Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Garcia EP; Department of Medical Oncology and.
  • Curran CR; Department of Medical Oncology and.
  • Hwang JH; Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Mayhew DL; Department of Medical Oncology and.
  • Nag A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Thorner AR; Department of Medical Oncology and.
  • Börcsök J; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Sztupinszki Z; Department of Medical Oncology and.
  • Pan CX; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Bellmunt J; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Kwiatkowski DJ; Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Sonpavde GP; Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Van Allen EM; VA Boston Healthcare System, Harvard Medical School, West Roxbury, Massachusetts, USA.
  • Mouw KW; Division of Hematology and Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
J Clin Invest ; 131(22)2021 11 15.
Article em En | MEDLINE | ID: mdl-34554931
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Amplificação de Genes / Proteínas Proto-Oncogênicas c-raf / Quinases de Proteína Quinase Ativadas por Mitógeno Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Amplificação de Genes / Proteínas Proto-Oncogênicas c-raf / Quinases de Proteína Quinase Ativadas por Mitógeno Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article