Safety and efficacy of using heat-killed <i>Lactobacillus plantarum</i> L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora.

Nakai, Hiroko; Murosaki, Shinji; Yamamoto, Yoshihiro; Furutani, Michiko; Matsuoka, Rumiko; Hirose, Yoshitaka

Safety and efficacy of using heat-killed Lactobacillus plantarum L-137: High-dose and long-term use effects on immune-related safety and intestinal bacterial flora.

Nakai, Hiroko; Murosaki, Shinji; Yamamoto, Yoshihiro; Furutani, Michiko; Matsuoka, Rumiko; Hirose, Yoshitaka.

Afiliação

Nakai H; Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan.
Murosaki S; Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan.
Yamamoto Y; Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan.
Furutani M; Wakamatsukawada Clinic, Tokyo, Japan.
Matsuoka R; Wakamatsukawada Clinic, Tokyo, Japan.
Hirose Y; Ingredient Research Division, Research and Development Institute, House Wellness Foods Corp, Itami, Japan.

J Immunotoxicol ; 18(1): 127-135, 2021 12.

Article em En | MEDLINE | ID: mdl-34559598

Assuntos

Microbioma Gastrointestinal; Lactobacillus plantarum; Probióticos; Animais; Temperatura Alta; Humanos

Palavras-chave

Bacteroidetes; Firmicutes; Heat-killed bacteria; Lactobacillus plantarum L-137; T-cell proliferation; adverse event; microbiota; safety; short-chain fatty acids

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Probióticos / Lactobacillus plantarum / Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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