Comparative Physicochemical Analysis among 1,4-Butanediol Diglycidyl Ether Cross-Linked Hyaluronic Acid Dermal Fillers.
Gels
; 7(3)2021 Sep 11.
Article
em En
| MEDLINE
| ID: mdl-34563025
ABSTRACT
(1) Background:
Injectable hyaluronic acid (HA) dermal fillers are used in several chirurgical practices and in aesthetic medicine. HA filler stability can be enhanced through different cross-linking technologies; one of the most frequently cross-linker used is 1,4-butanediol diglycidyl ether (BDDE), also present in the HA-BDDE dermal filler family of the company Matex Lab S.p.A. (Brindisi, Italy). Our overview is focused on their characterization, drawing a correlation between matrix structure, rheological and physicochemical properties related to their cross-linking technologies. (2)Methods:
Four different injectable HA hydrogels were characterized through optical microscopic examination and rheological behavior investigation. (3)Results:
The cross-linked HA dermal fillers showed a fibrous "spiderweb-like" matrix structure and an elastic and solid-like profile. (4)Conclusions:
The comparative analysis represents a preliminary characterization of these injectable medical devices in order to identify their best field of application.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article