3-methyadenine inhibits lipopolysaccharides-induced pulmonary inflammation at the early stage of silicosis via blocking NF-&#954;B signaling pathway.

Zhang, Yujing; Huang, Shuai; Tan, Shiyi; Chen, Mingke; Yang, Shang; Chen, Shi

3-methyadenine inhibits lipopolysaccharides-induced pulmonary inflammation at the early stage of silicosis via blocking NF-κB signaling pathway.

Zhang, Yujing; Huang, Shuai; Tan, Shiyi; Chen, Mingke; Yang, Shang; Chen, Shi.

Afiliação

Zhang Y; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.
Huang S; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.
Tan S; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.
Chen M; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.
Yang S; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.
Chen S; Key Laboratory of Molecular Epidemiology of Hunan Province, 12568Hunan Normal University, Changsha, Hunan Province, China.

Toxicol Ind Health ; 37(11): 662-673, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34565256

Assuntos

Nucleotídeos de Adenina/farmacologia; Lipopolissacarídeos/metabolismo; NF-kappa B/metabolismo; Pneumonia/prevenção & controle; Silicose/prevenção & controle; Animais; China; Humanos; Inflamação/prevenção & controle; Masculino; Camundongos; Camundongos Endogâmicos BALB C

Palavras-chave

3-MA; NF-κB; Silicosis; alveolar macrophages; inflammatory responses

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / Silicose / Nucleotídeos de Adenina / Lipopolissacarídeos / NF-kappa B Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male País como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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