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Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents.
Berghausen, Eva M; Janssen, Wiebke; Vantler, Marius; Gnatzy-Feik, Leoni L; Krause, Max; Behringer, Arnica; Joseph, Christine; Zierden, Mario; Freyhaus, Henrik Ten; Klinke, Anna; Baldus, Stephan; Alcazar, Miguel A; Savai, Rajkumar; Pullamsetti, Soni Savai; Wong, Dickson Wl; Boor, Peter; Zhao, Jean J; Schermuly, Ralph T; Rosenkranz, Stephan.
Afiliação
  • Berghausen EM; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Janssen W; Center for Molecular Medicine Cologne (CMMC) and.
  • Vantler M; Cologne Cardiovascular Research Center (CCRC), University of Cologne, Cologne, Germany.
  • Gnatzy-Feik LL; Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
  • Krause M; University of Giessen and Marburg Lung Center (UGMLC), and German Centre for Lung Research (DZL), Giessen, Germany.
  • Behringer A; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Joseph C; Center for Molecular Medicine Cologne (CMMC) and.
  • Zierden M; Cologne Cardiovascular Research Center (CCRC), University of Cologne, Cologne, Germany.
  • Freyhaus HT; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Klinke A; Center for Molecular Medicine Cologne (CMMC) and.
  • Baldus S; Cologne Cardiovascular Research Center (CCRC), University of Cologne, Cologne, Germany.
  • Alcazar MA; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Savai R; Center for Molecular Medicine Cologne (CMMC) and.
  • Pullamsetti SS; Cologne Cardiovascular Research Center (CCRC), University of Cologne, Cologne, Germany.
  • Wong DW; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Boor P; Center for Molecular Medicine Cologne (CMMC) and.
  • Zhao JJ; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
  • Schermuly RT; Center for Molecular Medicine Cologne (CMMC) and.
  • Rosenkranz S; Department of Cardiology, Heart Center at the University of Cologne, Cologne, Germany.
J Clin Invest ; 131(19)2021 10 01.
Article em En | MEDLINE | ID: mdl-34596056
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Classe Ia de Fosfatidilinositol 3-Quinase / Inibidores de Fosfoinositídeo-3 Quinase / Hipertensão Pulmonar Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Animals / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Classe Ia de Fosfatidilinositol 3-Quinase / Inibidores de Fosfoinositídeo-3 Quinase / Hipertensão Pulmonar Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Animals / Humans / Infant / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article