Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from <i>p</i>-tyramine.

Niwa, Toshiro; Arima, Juri; Michihiro, Yurina

Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine.

Niwa, Toshiro; Arima, Juri; Michihiro, Yurina.

Afiliação

Niwa T; School of Pharmacy, Shujitsu University, Okayama, Japan.
Arima J; School of Pharmacy, Shujitsu University, Okayama, Japan.
Michihiro Y; School of Pharmacy, Shujitsu University, Okayama, Japan.

Xenobiotica ; 51(11): 1229-1235, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34605737

Assuntos

Citocromo P-450 CYP2D6; Tiramina; Aminoácidos; Citocromo P-450 CYP2D6/genética; Dopamina; Paroxetina; Inibidores Seletivos de Recaptação de Serotonina

Palavras-chave

CYP2D6; dopamine formation; fluphenazine; genetic polymorphism; milnacipran; selective serotonin reuptake inhibitor (SSRI)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiramina / Citocromo P-450 CYP2D6 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiramina / Citocromo P-450 CYP2D6 Idioma: En Ano de publicação: 2021 Tipo de documento: Article