Your browser doesn't support javascript.
loading
Long-term aircraft noise exposure and risk of hypertension in the Nurses' Health Studies.
Kim, Chloe S; Grady, Stephanie T; Hart, Jaime E; Laden, Francine; VoPham, Trang; Nguyen, Daniel D; Manson, JoAnn E; James, Peter; Forman, John P; Rexrode, Kathryn M; Levy, Jonathan I; Peters, Junenette L.
Afiliação
  • Kim CS; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA; Electric Power Research Institute (EPRI), Palo Alto, CA, USA.
  • Grady ST; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA. Electronic address: sgrady@bu.edu.
  • Hart JE; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Exposure, Epidemiology and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Laden F; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Exposure, Epidemiology and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology
  • VoPham T; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Epidemiology Program, Division of Public Health Sciences, Fred Hutchinson C
  • Nguyen DD; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
  • Manson JE; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard M
  • James P; Exposure, Epidemiology and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Division of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Insti
  • Forman JP; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Rexrode KM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Division of Women's Health, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Levy JI; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
  • Peters JL; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
Environ Res ; 207: 112195, 2022 05 01.
Article em En | MEDLINE | ID: mdl-34627796
ABSTRACT

BACKGROUND:

Aircraft noise can affect populations living near airports. Chronic exposure to aircraft noise has been associated with cardiovascular disease, including hypertension. However, previous studies have been limited in their ability to characterize noise exposures over time and to adequately control for confounders.

OBJECTIVES:

The aim of this study was to examine the association between aircraft noise and incident hypertension in two cohorts of female nurses, using aircraft noise exposure estimates with high spatial resolution over a 20-year period.

METHODS:

We obtained contour maps of modeled aircraft noise levels over time for 90 U.S. airports and linked them with geocoded addresses of participants in the Nurses' Health Study (NHS) and Nurses' Health Study II (NHS II) to assign noise exposure for 1994-2014 and 1995-2013, respectively. We used time-varying Cox proportional hazards models to estimate hypertension risk associated with time-varying noise exposure (dichotomized at 45 and 55 dB(A)), adjusting for fixed and time-varying confounders. Results from both cohorts were pooled via random effects meta-analysis.

RESULTS:

In meta-analyses of parsimonious and fully-adjusted models with aircraft noise dichotomized at 45 dB(A), hazard ratios (HR) for hypertension incidence were 1.04 (95% CI 1.00, 1.07) and 1.03 (95% CI 0.99, 1.07), respectively. When dichotomized at 55 dB(A), HRs were 1.10 (95% CI 1.01, 1.19) and 1.07 (95% CI 0.98, 1.15), respectively. After conducting fully-adjusted sensitivity analyses limited to years in which particulate matter (PM) was obtained, we observed similar findings. In NHS, the PM-unadjusted HR was 1.01 (95% CI 0.90, 1.14) and PM-adjusted HR was 1.01 (95% CI 0.89, 1.14); in NHS II, the PM-unadjusted HR was 1.08 (95% CI 0.96, 1.22) and the PM-adjusted HR was 1.08 (95% CI 0.95, 1.21). Overall, in these cohorts, we found marginally suggestive evidence of a positive association between aircraft noise exposure and hypertension.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão / Enfermeiras e Enfermeiros Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão / Enfermeiras e Enfermeiros Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article