2020 WHO Classification of Female Genital Tumors.
Geburtshilfe Frauenheilkd
; 81(10): 1145-1153, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34629493
ABSTRACT
The 2020 WHO classification is focused on the distinction between HPV-associated and HPV-independent squamous cell carcinoma of the lower female genital organs. Differentiating according to HPV association does not replace the process of grading; however, the WHO classification does not recommend any specific grading system. VIN are also differentiated according to whether they are HPV(p16)-associated. HPV-independent adenocarcinoma (AC) of the cervix uteri has an unfavorable prognosis. Immunohistochemical p16 expression is considered to be a surrogate marker for HPV association. HPV-associated AC of the cervix uteri is determined using the prognostically relevant Silva pattern.
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MEDLINE
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En
Ano de publicação:
2021
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Article