Semiparametric regression analysis of clustered interval-censored failure time data with a cured subgroup.
Stat Med
; 40(30): 6918-6930, 2021 12 30.
Article
em En
| MEDLINE
| ID: mdl-34634837
ABSTRACT
This article discusses regression analysis of clustered interval-censored failure time data in the presence of a cured fraction or subgroup. Such data often occur in many areas, including epidemiological studies, medical studies, and social sciences. For the problem, a class of semiparametric transformation nonmixture cure models is presented and for estimation, the maximum likelihood estimation procedure is derived. For the implementation of the proposed method, we develop a novel EM algorithm based on a Poisson variable-based augmentation. An extensive simulation study is conducted and suggests that the proposed approach works well in practical situations. Finally the method is applied to an example that motivated this study.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Algoritmos
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article