Universal Properties and Specificities of the ß<sub>2</sub>-Adrenergic Receptor-G<sub>s</sub> Protein Complex Activation Mechanism Revealed by All-Atom Molecular Dynamics Simulations.

Mitra, Argha; Sarkar, Arijit; Borics, Attila

Universal Properties and Specificities of the ß₂-Adrenergic Receptor-G_s Protein Complex Activation Mechanism Revealed by All-Atom Molecular Dynamics Simulations.

Mitra, Argha; Sarkar, Arijit; Borics, Attila.

Afiliação

Mitra A; Laboratory of Chemical Biology, Institute of Biochemistry, Biological Research Centre, 62. Temesvári krt., H-6726 Szeged, Hungary.
Sarkar A; Theoretical Medicine Doctoral School, Faculty of Medicine, University of Szeged, 97. Tisza L. krt., H-6722 Szeged, Hungary.
Borics A; Laboratory of Chemical Biology, Institute of Biochemistry, Biological Research Centre, 62. Temesvári krt., H-6726 Szeged, Hungary.

Int J Mol Sci ; 22(19)2021 Sep 27.

Article em En | MEDLINE | ID: mdl-34638767

Assuntos

Simulação de Dinâmica Molecular; Receptores Adrenérgicos beta 2/química; Receptores Opioides mu/química; Motivos de Aminoácidos; Humanos; Domínios Proteicos

Palavras-chave

GPCR; activation mechanism; adrenergic; molecular dynamics; signal transduction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Adrenérgicos beta 2 / Receptores Opioides mu / Simulação de Dinâmica Molecular Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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