The Lung Microbiome during Health and Disease.
Int J Mol Sci
; 22(19)2021 Oct 08.
Article
em En
| MEDLINE
| ID: mdl-34639212
ABSTRACT
Healthy human lungs have traditionally been considered to be a sterile organ. However, culture-independent molecular techniques have reported that large numbers of microbes coexist in the lung and airways. The lungs harbor diverse microbial composition that are undetected by previous approaches. Many studies have found significant differences in microbial composition between during health and respiratory disease. The lung microbiome is likely to not only influence susceptibility or causes of diseases but be affected by disease activities or responses to treatment. Although lung microbiome research has some limitations from study design to reporting, it can add further dimensionality to host-microbe interactions. Moreover, there is a possibility that extending understanding to the lung microbiome with new multiple omics approaches would be useful for developing both diagnostic and prognostic biomarkers for respiratory diseases in clinical settings.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Interações Hospedeiro-Patógeno
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Microbiota
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Pulmão
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Pneumopatias
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article