Effects of low-level light therapy on dentin hypersensitivity: a systematic review and meta-analysis.
Clin Oral Investig
; 25(12): 6571-6595, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34642786
ABSTRACT
OBJECTIVE:
To investigate the treatment efficacy of low-level light therapy on dentin hypersensitivity. MATERIALS ANDMETHODS:
Following the PRISMA guideline, six electronic databases supplemented with bibliographies were searched till December 2020. Two reviewers performed the screenings independently with a reliability assessment. Studies fulfilling the pre-registered eligibility criteria were included for risk-of-bias assessment and data synthesis.RESULTS:
Thirty-five articles ultimately informed this systematic review based on the eligibility criteria and underwent risk-of-bias assessment (ĸ = 0.86). Quantitative results were deduced by meta-analysis of 20 randomised controlled trials LLLT showed favourable outcomes compared to placebos for immediate (SMD 1.09, 95% CI 0.47 to 1.70), interim (SMD 1.32, 95% CI 0.41 to 2.23), and persistent efficacies (SMD 2.86, 95% CI 1.98 to 3.74). However, substantial heterogeneity existed among included studies (I2 64-95%). Regarding comparisons with other desensitising strategies, LLLT showed no significant benefits in DH alleviation over others except fluorides for interim efficacy (SMD 0.31, 95% CI 0.10 to 0.52) and persistent efficacy (SMD 0.45, 95% CI 0.03 to 0.86).CONCLUSIONS:
This systematic review shows that LLLT has positive immediate, interim, and persistent DH-treatment efficacies compared with placebo. No superior treatment effects of LLLT were observed except fluoride agent use. Further studies are warranted-RCTs with low risk of bias, consistent technical settings, comprehensive assessments, and long follow-up periods. CLINICAL RELEVANCE This systematic review bridges a critical research gap by analysing clinical evidence in the DH-alleviating efficacy of LLLT in comparison with placebo and other in-office desensitising strategies.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia com Luz de Baixa Intensidade
/
Sensibilidade da Dentina
Tipo de estudo:
Clinical_trials
/
Guideline
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Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article