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Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases.
Raman, Vishnu; Van Dessel, Nele; Hall, Christopher L; Wetherby, Victoria E; Whitney, Samantha A; Kolewe, Emily L; Bloom, Shoshana M K; Sharma, Abhinav; Hardy, Jeanne A; Bollen, Mathieu; Van Eynde, Aleyde; Forbes, Neil S.
Afiliação
  • Raman V; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Van Dessel N; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
  • Hall CL; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Wetherby VE; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
  • Whitney SA; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Kolewe EL; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
  • Bloom SMK; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
  • Sharma A; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Hardy JA; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Bollen M; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Van Eynde A; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
  • Forbes NS; Department of Chemistry, University of Massachusetts, Amherst, Amherst, MA, USA.
Nat Commun ; 12(1): 6116, 2021 10 21.
Article em En | MEDLINE | ID: mdl-34675204
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Salmonella / Sistemas de Liberação de Medicamentos / Carcinoma Hepatocelular / Caspase 3 / Neoplasias Hepáticas / Neoplasias Pulmonares Tipo de estudo: Evaluation_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Salmonella / Sistemas de Liberação de Medicamentos / Carcinoma Hepatocelular / Caspase 3 / Neoplasias Hepáticas / Neoplasias Pulmonares Tipo de estudo: Evaluation_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article