Clomiphene Citrate Shows Effective and Sustained Antimicrobial Activity against <i>Mycobacterium abscessus</i>.

Lee, Da-Gyum; Hwang, Yoo-Hyun; Park, Eun-Jin; Kim, Jung-Hyun; Ryoo, Sung-Weon

Clomiphene Citrate Shows Effective and Sustained Antimicrobial Activity against Mycobacterium abscessus.

Lee, Da-Gyum; Hwang, Yoo-Hyun; Park, Eun-Jin; Kim, Jung-Hyun; Ryoo, Sung-Weon.

Afiliação

Lee DG; Center for Clinical Research, Masan National Tuberculosis Hospital, Korea Centers for Disease Control and Prevention, Changwon 51755, Korea.
Hwang YH; Center for Clinical Research, Masan National Tuberculosis Hospital, Korea Centers for Disease Control and Prevention, Changwon 51755, Korea.
Park EJ; Center for Clinical Research, Masan National Tuberculosis Hospital, Korea Centers for Disease Control and Prevention, Changwon 51755, Korea.
Kim JH; Infection Control Convergence Research Center, Chungnam National University College of Medicine, Daejeon 35015, Korea.
Ryoo SW; Division of Intractable Diseases, Center for Biomedical Sciences, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongju 28159, Korea.

Int J Mol Sci ; 22(20)2021 Oct 13.

Article em En | MEDLINE | ID: mdl-34681686

Assuntos

Clomifeno/farmacologia; Macrófagos; Infecções por Mycobacterium não Tuberculosas/tratamento farmacológico; Mycobacterium abscessus/efeitos dos fármacos; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Clomifeno/uso terapêutico; Reposicionamento de Medicamentos; Humanos; Células THP-1

Palavras-chave

Mycobacterium abscessus; clomiphene citrate; drug repurposing; drug resistance; non-tuberculosis mycobacteria

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Clomifeno / Mycobacterium abscessus / Macrófagos / Infecções por Mycobacterium não Tuberculosas Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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