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Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
You, Xiaona; Liu, Fabao; Binder, Moritz; Vedder, Alexis; Lasho, Terra; Wen, Zhi; Gao, Xin; Flietner, Evan; Rajagopalan, Adhithi; Zhou, Yun; Finke, Christy; Mangaonkar, Abhishek; Liao, Ruiqi; Kong, Guangyao; Ranheim, Erik A; Droin, Nathalie; Hunter, Anthony M; Nikolaev, Sergey; Balasis, Maria; Abdel-Wahab, Omar; Levine, Ross L; Will, Britta; Nadiminti, Kalyan Vara Ganesh; Yang, David; Geissler, Klaus; Solary, Eric; Xu, Wei; Padron, Eric; Patnaik, Mrinal M; Zhang, Jing.
Afiliação
  • You X; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Liu F; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Binder M; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
  • Vedder A; Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Lasho T; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
  • Wen Z; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Gao X; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Flietner E; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Rajagopalan A; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Zhou Y; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Finke C; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
  • Mangaonkar A; Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
  • Liao R; Department of Cell and Regenerative Biology and.
  • Kong G; McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Ranheim EA; Department of Pathology and Laboratory Medicine, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI.
  • Droin N; INSERM U981, Gustave Roussy Cancer Center, Villejuif, France.
  • Hunter AM; Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Nikolaev S; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.
  • Balasis M; INSERM U981, Gustave Roussy Cancer Center, Villejuif, France.
  • Abdel-Wahab O; Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Levine RL; Human Oncology and Pathogenesis Program.
  • Will B; Leukemia Service, Department of Medicine.
  • Nadiminti KVG; Center for Hematologic Malignancies, and.
  • Yang D; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Geissler K; Human Oncology and Pathogenesis Program.
  • Solary E; Leukemia Service, Department of Medicine.
  • Xu W; Center for Hematologic Malignancies, and.
  • Padron E; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Patnaik MM; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.
  • Zhang J; Division of Hematology, Medical Oncology and Palliative Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Blood ; 139(7): 1066-1079, 2022 02 17.
Article em En | MEDLINE | ID: mdl-34699595
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Leucemia Mielomonocítica Crônica / Leucemia Mieloide Aguda / Modelos Animais de Doenças / Microambiente Tumoral / GTP Fosfo-Hidrolases / Proteínas de Membrana / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Leucemia Mielomonocítica Crônica / Leucemia Mieloide Aguda / Modelos Animais de Doenças / Microambiente Tumoral / GTP Fosfo-Hidrolases / Proteínas de Membrana / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article