Accelerated Maturation, Exhaustion, and Senescence of T cells in 22q11.2 Deletion Syndrome.

Smetanova, Jitka; Milota, Tomas; Rataj, Michal; Bloomfield, Marketa; Sediva, Anna; Klocperk, Adam

Smetanova, Jitka; Milota, Tomas; Rataj, Michal; Bloomfield, Marketa; Sediva, Anna; Klocperk, Adam.

Afiliação

Smetanova J; Department of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84, 150 06, Prague, Czech Republic.
Milota T; Department of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84, 150 06, Prague, Czech Republic.
Rataj M; Department of Paediatric and Adult Rheumatology, University Hospital Motol, Prague, Czech Republic.
Bloomfield M; Department of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84, 150 06, Prague, Czech Republic.
Sediva A; Department of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84, 150 06, Prague, Czech Republic.
Klocperk A; Department of Paediatrics, First Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.

J Clin Immunol ; 42(2): 274-285, 2022 02.

Article em En | MEDLINE | ID: mdl-34716533

Assuntos

Síndrome de DiGeorge; Adolescente; Linfócitos T CD4-Positivos; Diferenciação Celular; Criança; Pré-Escolar; Síndrome de DiGeorge/genética; Humanos; Lactente; Recém-Nascido; Contagem de Linfócitos; Células Th17

Palavras-chave

22q11.2 deletion syndrome; CD57; DiGeorge syndrome; PD1; T cells; differentiation; immunodeficiency; maturation; thymus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de DiGeorge Limite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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