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Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor.
Desch, Michael; Wunderlich, Glen; Goettel, Markus; Goetz, Sophia; Liesenfeld, Karl-Heinz; Chan, Tom S; Rosenbrock, Holger; Sennewald, Regina; Link, Jasmin; Keller, Sascha; Wind, Sven.
Afiliação
  • Desch M; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany. michael.desch@boehringer-ingelheim.com.
  • Wunderlich G; Boehringer Ingelheim Canada Ltd, Burlington, ON, Canada.
  • Goettel M; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany.
  • Goetz S; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Liesenfeld KH; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Chan TS; Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT, USA.
  • Rosenbrock H; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Sennewald R; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Link J; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Keller S; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
  • Wind S; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an der Riss, Baden Württemberg, Germany.
Eur J Drug Metab Pharmacokinet ; 47(1): 91-103, 2022 Jan.
Article em En | MEDLINE | ID: mdl-34716565
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Rifampina / Esquizofrenia / Itraconazol / Nootrópicos / Inibidores do Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Rifampina / Esquizofrenia / Itraconazol / Nootrópicos / Inibidores do Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article