Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum.

Nakafero, Georgina; Grainge, Matthew J; Card, Tim; Taal, Maarten W; Aithal, Guruprasad P; Zhang, Weiya; Doherty, Michael; Fox, Christopher P; Mallen, Christian D; Abhishek, Abhishek

Nakafero, Georgina; Grainge, Matthew J; Card, Tim; Taal, Maarten W; Aithal, Guruprasad P; Zhang, Weiya; Doherty, Michael; Fox, Christopher P; Mallen, Christian D; Abhishek, Abhishek.

Afiliação

Nakafero G; Academic Rheumatology.
Grainge MJ; Population and Lifespan Sciences.
Card T; Population and Lifespan Sciences.
Taal MW; Nottingham Digestive Diseases Centre, School of Medicine.
Aithal GP; Centre for Kidney Research and Innovation, University on Nottingham.
Zhang W; Nottingham Digestive Diseases Centre, School of Medicine.
Doherty M; NIHR Nottingham BRC, Nottingham University Hospitals NHS Trust and the University of Nottingham.
Fox CP; Academic Rheumatology.
Mallen CD; Academic Rheumatology.
Abhishek A; Department of Haematology, Nottingham University Hospital NHS Trust, Nottingham.

Rheumatology (Oxford) ; 61(7): 2783-2791, 2022 07 06.

Article em En | MEDLINE | ID: mdl-34718430

Assuntos

Testes Hematológicos; Estudos de Coortes; Humanos; Leflunomida/uso terapêutico; Prognóstico

Palavras-chave

drug toxicity; leflunomide; monitoring; psoriatic arthritis; rheumatoid arthritis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Hematológicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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