[Identification of Synthetic Cannabinoid New Psychoactive Substances 4F-MDMB-BUTINACA and MDMB-4en-PINACA].
Fa Yi Xue Za Zhi
; 37(4): 505-510, 2021 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-34726003
ABSTRACT
ABSTRACT Objective To establish a method that combines a series of techniques including Fourier transform infrared spectrum ï¼FTIRï¼, gas chromatography-mass spectrometry ï¼GC-MSï¼, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy ï¼NMRï¼ for identification of unknown substances. Methods The unknown samples ï¼off-white powder and yellow crystalï¼ seized in the actual cases were detected by FTIR, GC-MS ï¼methanol as solventï¼, high resolution mass spectrometry ï¼methanol as solventï¼ and NMR ï¼deuterated methanol as solventï¼. Results The mass spectrum characteristic ions m/z of the main components in the samples measured by GC-MS were 219 ï¼base peakï¼, 363, 307, 304, 275, 145, 131 and 213 ï¼base peakï¼, 357, 301, 298, 269, 185, 171, 145 and 131, respectively. The accurate mass numbers [M+H]+ measured by high resolution mass spectrometry were 364.203 61 and 358.212 34, respectively. The unknown samples were identified as synthetic cannabinoid new psychoactive substances 4F-MDMB-BUTINACA and MDMB-4en-PINACA after data consultation and database retrieval and comparison, combined with infrared analysis and mass spectrometry data analysis, and their structures were confirmed by 1H-NMR. Conclusion The established multi-technology joint identification method can be used to identify 4F-MDMB-BUTINACA and MDMB-4en-PINACA in unknown samples. This method is fast, convenient, accurate, reliable and practical, and can provide reference for the identification of cases involving such substances in the future.
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Base de dados:
MEDLINE
Assunto principal:
Canabinoides
/
Drogas Ilícitas
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Idioma:
Zh
Ano de publicação:
2021
Tipo de documento:
Article