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Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant.
Al-Moubarak, Ehab; Shiels, Holly A; Zhang, Yihong; Du, Chunyun; Hanington, Oliver; Harmer, Stephen C; Dempsey, Christopher E; Hancox, Jules C.
Afiliação
  • Al-Moubarak E; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK.
  • Shiels HA; Division of Cardiovascular Sciences, University of Manchester, Manchester, UK.
  • Zhang Y; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK.
  • Du C; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK.
  • Hanington O; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK.
  • Harmer SC; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK.
  • Dempsey CE; School of Biochemistry, University of Bristol, Bristol, UK.
  • Hancox JC; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, BS8 1TD, UK. jules.hancox@bristol.ac.uk.
Cell Mol Life Sci ; 78(23): 7899-7914, 2021 Dec.
Article em En | MEDLINE | ID: mdl-34727194
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenantrenos / Fenômenos Eletrofisiológicos / Simulação de Acoplamento Molecular / Canal de Potássio ERG1 / Mutação Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenantrenos / Fenômenos Eletrofisiológicos / Simulação de Acoplamento Molecular / Canal de Potássio ERG1 / Mutação Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article