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Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome.
Lam, Kathy N; Spanogiannopoulos, Peter; Soto-Perez, Paola; Alexander, Margaret; Nalley, Matthew J; Bisanz, Jordan E; Nayak, Renuka R; Weakley, Allison M; Yu, Feiqiao B; Turnbaugh, Peter J.
Afiliação
  • Lam KN; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Spanogiannopoulos P; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Soto-Perez P; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Alexander M; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Nalley MJ; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Bisanz JE; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Nayak RR; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Weakley AM; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA; Stanford ChEM-H: Chemistry, Engineering and Medicine for Human Health, Stanford University, Stanford, CA 94305, USA.
  • Yu FB; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.
  • Turnbaugh PJ; Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: peter.turnbaugh@ucsf.edu.
Cell Rep ; 37(5): 109930, 2021 11 02.
Article em En | MEDLINE | ID: mdl-34731631
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deleção Cromossômica / Cromossomos Bacterianos / Bacteriófago M13 / Escherichia coli / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas / Microbioma Gastrointestinal / Edição de Genes / Proteína 9 Associada à CRISPR Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deleção Cromossômica / Cromossomos Bacterianos / Bacteriófago M13 / Escherichia coli / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas / Microbioma Gastrointestinal / Edição de Genes / Proteína 9 Associada à CRISPR Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article