MEK1/2 is a bottleneck that induces cancer stem cells to activate the PI3K/AKT pathway.

Hassan, Ghmkin; Afify, Said M; Du, Juan; Nawara, Hend M; Sheta, Mona; Monzur, Sadia; Zahra, Maram H; Abu Quora, Hagar A; Mansour, Hager; El-Ghlban, Samah; Uesaki, Ryo; Seno, Akimasa; Seno, Masaharu

Hassan, Ghmkin; Afify, Said M; Du, Juan; Nawara, Hend M; Sheta, Mona; Monzur, Sadia; Zahra, Maram H; Abu Quora, Hagar A; Mansour, Hager; El-Ghlban, Samah; Uesaki, Ryo; Seno, Akimasa; Seno, Masaharu.

Afiliação

Hassan G; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan; Department of Genomic Oncology and Oral Medicine, Graduate School of Biomedical and Health Sc
Afify SM; Division of Biochemistry, Chemistry Department, Faculty of Science, Menoufia University, Shebin El Koum-Menoufia 32511, Egypt.
Du J; Department of Cancer Institute, Shanxi Provincial Cancer Hospital, Taiyuan, PR China.
Nawara HM; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan.
Sheta M; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan; Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt.
Monzur S; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan.
Zahra MH; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan.
Abu Quora HA; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan; Cytology, Histology and Histochemistry, Zoology Department, Faculty of Science, Menoufia Univ
Mansour H; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan.
El-Ghlban S; Division of Biochemistry, Chemistry Department, Faculty of Science, Menoufia University, Shebin El Koum-Menoufia 32511, Egypt.
Uesaki R; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan.
Seno A; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan; The Laboratory of Natural Food and Medicine, Co Ltd, Okayama 700-8530, Japan.
Seno M; Laboratory of Nano-Biotechnology, Department of Biotechnology and Drug Discovery, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 700-8530, Japan. Electronic address: mseno@okayama-u.ac.jp.