Uncomplicated oocyte donation pregnancies display an elevated CD163-positive type 2 macrophage load in the decidua, which is associated with fetal-maternal HLA mismatches.

Tian, Xuezi; Aiyer, Kaveri T S; Kapsenberg, Johanna M; Roelen, Dave L; van der Hoorn, Marie-Louise; Eikmans, Michael

Tian, Xuezi; Aiyer, Kaveri T S; Kapsenberg, Johanna M; Roelen, Dave L; van der Hoorn, Marie-Louise; Eikmans, Michael.

Afiliação

Tian X; Department of Obstetrics and Gynecology, Leiden University Medical Center, Leiden, Netherlands.
Aiyer KTS; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Kapsenberg JM; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Roelen DL; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
van der Hoorn ML; Department of Obstetrics and Gynecology, Leiden University Medical Center, Leiden, Netherlands.
Eikmans M; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.

Am J Reprod Immunol ; 87(1): e13511, 2022 01.

Article em En | MEDLINE | ID: mdl-34738274

Assuntos

Antígenos CD/metabolismo; Antígenos de Diferenciação Mielomonocítica/metabolismo; Decídua/metabolismo; Macrófagos/metabolismo; Doação de Oócitos; Receptores de Superfície Celular/metabolismo; Adulto; Feminino; Humanos; Tolerância Imunológica; Gravidez

Palavras-chave

HLA antigens; decidua; macrophages; oocyte donation; pregnancy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos de Diferenciação Mielomonocítica / Antígenos CD / Receptores de Superfície Celular / Doação de Oócitos / Decídua / Macrófagos Tipo de estudo: Risk_factors_studies Limite: Adult / Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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