FOXM1 accelerates wound healing in diabetic foot ulcer by inducing M2 macrophage polarization through a mechanism involving SEMA3C/NRP2/Hedgehog signaling.

Yang, Yang; Zhang, Bo; Yang, Yufan; Peng, Bibo; Ye, Rui

Yang, Yang; Zhang, Bo; Yang, Yufan; Peng, Bibo; Ye, Rui.

Afiliação

Yang Y; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China; Department of General Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
Zhang B; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
Yang Y; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
Peng B; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
Ye R; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China. Electronic ad

Diabetes Res Clin Pract ; 184: 109121, 2022 Feb.

Article em En | MEDLINE | ID: mdl-34742786

Assuntos

Diabetes Mellitus; Pé Diabético; Animais; Diabetes Mellitus/metabolismo; Pé Diabético/genética; Proteína Forkhead Box M1; Proteínas Hedgehog/genética; Proteínas Hedgehog/metabolismo; Proteínas Hedgehog/farmacologia; Humanos; Macrófagos/metabolismo; Ratos; Transdução de Sinais; Cicatrização/genética

Palavras-chave

Class-3 semaphorins; Diabetic foot ulcer; Fibroblasts; Forkhead box M1; Hedgehog signaling pathway; M2 polarization; Macrophages; Neuropilin-2; Wound healing

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pé Diabético / Diabetes Mellitus Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google