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Sequenced Breakpoints of Crossover Suppressor/Inversion qC1.
Edgley, Mark L; Flibotte, Stephane; Moerman, Donald G.
Afiliação
  • Edgley ML; Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada.
  • Flibotte S; UBC/LSI Bioinformatics Facility, University of British Columbia, Vancouver, British Columbia, Canada.
  • Moerman DG; Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada.
MicroPubl Biol ; 20212021.
Article em En | MEDLINE | ID: mdl-34746683
ABSTRACT
We used whole-genome sequencing (WGS) data from a number of balanced lethal strains in Caenorhabditis elegans to show that the crossover suppressor qC1 is an inversion. The rearrangement is complex, with a large primary inversion that contains several other smaller inverted regions. The graphical representation below depicts these various qC1 rearrangements for ease of conceptualization. It is the simplest chromosomal structure compatible with the data currently available, but even then it is worth noting that the complexity of the qC1 chromosome can make the graphical reconstruction difficult to understand, and it may seem a bit like relativity theory or artwork from M.C. Escher (https//moa.byu.edu/m-c-eschers-relativity/).

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article