The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin-induced cardiotoxicity: A review.

Tabrizi, Fatemeh B; Yarmohammadi, Fatemeh; Hayes, A Wallace; Karimi, Gholamreza

Tabrizi, Fatemeh B; Yarmohammadi, Fatemeh; Hayes, A Wallace; Karimi, Gholamreza.

Afiliação

Tabrizi FB; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Yarmohammadi F; Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Hayes AW; Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Karimi G; Center for Environmental Occupational Risk Analysis and Management, College of Public Health, University of South Florida, Tampa, Florida, USA.

J Biochem Mol Toxicol ; 36(1): e22946, 2022 Jan.

Article em En | MEDLINE | ID: mdl-34747550

Assuntos

Berberina/uso terapêutico; Dioxóis/uso terapêutico; Doxorrubicina/efeitos adversos; Cardiopatias/enzimologia; Lignanas/uso terapêutico; Miocárdio/enzimologia; Sirtuína 1/metabolismo; Sirtuína 3/metabolismo; Animais; Cardiotoxicidade/tratamento farmacológico; Cardiotoxicidade/enzimologia; Doxorrubicina/farmacologia; Cardiopatias/induzido quimicamente; Cardiopatias/tratamento farmacológico; Humanos

Palavras-chave

SIRT1; SIRT3; apoptosis; cardiac injury; inflammation; oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Doxorrubicina / Lignanas / Dioxóis / Sirtuína 1 / Sirtuína 3 / Cardiopatias / Miocárdio Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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