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Biopsychosocial Rehabilitation for Inflammatory Arthritis and Osteoarthritis Patients: A Systematic Review and Meta-Analysis of Randomized Trials.
Pedersen, Morten B; Thinggaard, Peter; Geenen, Rinie; Rasmussen, Marianne U; Wit, Maarten De; March, Lyn; Mease, Philip; Choy, Ernest; Conaghan, Philip G; Simon, Lee; Hansen, Anne Faber; Tarp, Simon; Schiøttz-Christensen, Berit; Juhl, Carsten B; Nielsen, Sabrina M; Amris, Kirstine; Christensen, Robin.
Afiliação
  • Pedersen MB; University of Southern Denmark, Odense, and Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Thinggaard P; Spine Centre of Southern Denmark, Sygehus Lillebaelt Middelfart Sygehus, Middelfart, Denmark.
  • Geenen R; Utrecht University, Utrecht, The Netherlands.
  • Rasmussen MU; Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Wit M; Amsterdam University Medical Centre, Amsterdam, The Netherlands.
  • March L; University of Sydney, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
  • Mease P; Swedish Medical Center/Providence St Joseph Health and University of Washington, Seattle.
  • Choy E; Cardiff University School of Medicine, Cardiff, UK.
  • Conaghan PG; University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds, UK.
  • Simon L; SDG LLC, Cambridge, Massachusetts.
  • Hansen AF; University Library of Southern Denmark, Odense, Denmark.
  • Tarp S; Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Schiøttz-Christensen B; Spine Centre of Southern Denmark, Sygehus Lillebaelt Middelfart Sygehus, Middelfart, Denmark.
  • Juhl CB; University of Southern Denmark, Odense, and Herlev and Gentofte Hospital, Copenhagen, Denmark.
  • Nielsen SM; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, and University of Southern Denmark, Odense University Hospital, Odense, Denmark.
  • Amris K; Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Christensen R; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, and University of Southern Denmark, Odense University Hospital, Odense, Denmark.
Arthritis Care Res (Hoboken) ; 75(2): 423-436, 2023 02.
Article em En | MEDLINE | ID: mdl-34748288
OBJECTIVE: To assess the benefits and harms associated with biopsychosocial rehabilitation in patients with inflammatory arthritis and osteoarthritis (OA). METHODS: We performed a systematic review and meta-analysis. Data were collected through electronic searches of Cochrane CENTRAL, MEDLINE, Embase, PsycInfo, and CINAHL databases up to March 2019. Trials examining the effect of biopsychosocial rehabilitation in adults with inflammatory arthritis and/or OA were considered eligible, excluding rehabilitation adjunct to surgery. The primary outcome for benefit was pain and total withdrawals for harm. RESULTS: Of the 27 trials meeting the eligibility criteria, 22 trials (3,750 participants) reported sufficient data to be included in the quantitative synthesis. For patient-reported outcome measures, biopsychosocial rehabilitation was slightly superior to control for pain relief (standardized mean difference [SMD] -0.19 [95% confidence interval (95% CI) -0.31, -0.07]), had a small effect on patient global assessment score (SMD -0.13 [95% CI -0.26, -0.00]), with no apparent effect on health-related quality of life, fatigue, self-reported disability/physical function, mental well-being, and reduction in pain intensity ≥30%. Clinician-measured outcomes displayed a small effect on observed disability/physical function (SMD -0.34 [95% CI -0.57, -0.10]), a large effect on physician global assessment score (SMD -0.72 [95% CI -1.18, -0.26]), and no effect on inflammation. No difference in harms existed in terms of the number of withdrawals, adverse events, or serious adverse events. CONCLUSION: Biopsychosocial rehabilitation produces a significant but clinically small beneficial effect on patient-reported pain among patients with inflammatory arthritis and OA, with no difference in harm. Methodologic weaknesses were observed in the included trials, suggesting low-to-moderate confidence in the estimates of effect.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite / Qualidade de Vida Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite / Qualidade de Vida Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article