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The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.
Bockaj, Irena; Martini, Tosca E I; de Camargo Magalhães, Eduardo S; Bakker, Petra L; Meeuwsen-de Boer, Tiny G J; Armandari, Inna; Meuleman, Saskia L; Mondria, Marin T; Stok, Colin; Kok, Yannick P; Bakker, Bjorn; Wardenaar, René; Seiler, Jonas; Broekhuis, Mathilde J C; van den Bos, Hilda; Spierings, Diana C J; Ringnalda, Femke C A; Clevers, Hans; Schüller, Ulrich; van Vugt, Marcel A T M; Foijer, Floris; Bruggeman, Sophia W M.
Afiliação
  • Bockaj I; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Martini TEI; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • de Camargo Magalhães ES; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Bakker PL; Glial Cell Biology Laboratory, Biomedical Sciences Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Meeuwsen-de Boer TGJ; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Armandari I; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Meuleman SL; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Mondria MT; Department of Histology and Cell Biology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
  • Stok C; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Kok YP; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Bakker B; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Wardenaar R; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Seiler J; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Broekhuis MJC; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • van den Bos H; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Spierings DCJ; iPSC/CRISPR facility, Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Ringnalda FCA; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Clevers H; iPSC/CRISPR facility, Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Schüller U; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • van Vugt MATM; Department of Ageing Biology/ERIBA, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Foijer F; Princess Máxima Center for Pediatric Oncology, Oncode Institute, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Bruggeman SWM; Princess Máxima Center for Pediatric Oncology, Oncode Institute, University Medical Center Utrecht, Utrecht, the Netherlands.
PLoS Genet ; 17(11): e1009868, 2021 11.
Article em En | MEDLINE | ID: mdl-34752469
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Histonas / Instabilidade Genômica / Replicação do DNA / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Histonas / Instabilidade Genômica / Replicação do DNA / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article