Does the Implementation of the PRO-IMPLANT Foundation Treatment Algorithm Improve the Outcome of Chronic Periprosthetic Knee Infections? Mid-Term Results of a Prospective Study. / Verbessert die Implementierung des PRO-IMPLANT Foundation Behandlungsalgorithmus die Therapie chronischer periprothetischer Knieprotheseninfektionen? Ergebnisse einer prospektiven Studie.
Z Orthop Unfall
; 161(3): 260-270, 2023 Jun.
Article
em En, De
| MEDLINE
| ID: mdl-34753193
ABSTRACT
BACKGROUND:
Several treatment options for chronic periprosthetic joint infections have been published in the current literature, with an on-going discussion to determine effective management algorithms.OBJECTIVES:
To compare outcomes of the two-stage exchange procedure in revision TKA prior to and after implementation of the PRO-IMPLANT Foundation treatment algorithm. The primary endpoints were defined as (i) revisions during the interval time, (ii) duration of the interval time and (iii) successful PJI eradication. MATERIAL ANDMETHODS:
Between 02/2013 and 09/2016, 122 patients were included in a single-centre cohort analysis. 55 patients were treated according to the previously used algorithm (K1) and 67 according to the PRO-IMPLANT Foundation algorithm (K2). A minimum follow-up period of 3 years was set as the inclusion criterion. Successful eradication of infection was defined in accordance with the consensus criteria by Diaz-Ledezma et al.RESULTS:
Successful eradication was achieved in 42 (67%) patients in K1 and 47 (85.5%) in K2 (p ≤ 0.005). The mean interval time was 88 days (range 51â-â353) in K1 and 52 days (range 42â-â126) in K2 (p ≤ 0.005). In K1, a mean of 0.8 (range 0â-â6) revisions were necessary during the interval period compared with 0.5 (range 0â-â4) in K2 (p = 0.066).CONCLUSION:
Implementation of the PRO-IMPLANT treatment algorithm led to significant improvement in the outcome of periprosthetic joint infections. During mid-term follow-up, infection eradication was highly successful, with decreases in the interval time as well as the number of revisions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Relacionadas à Prótese
/
Artroplastia do Joelho
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
De
/
En
Ano de publicação:
2023
Tipo de documento:
Article