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Synthesis, biological evaluation, and molecular docking studies of deoxygenated C-glycosides as LpxC inhibitors.
Dreger, Alexander; Hoff, Katharina; Agoglitta, Oriana; Bülbül, Emre F; Melesina, Jelena; Sippl, Wolfgang; Holl, Ralph.
Afiliação
  • Dreger A; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany.
  • Hoff K; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany.
  • Agoglitta O; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany.
  • Bülbül EF; Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany.
  • Melesina J; Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany.
  • Sippl W; Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany.
  • Holl R; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany. Electronic address: ralph.holl@chemie.uni-hamburg.de.
Bioorg Chem ; 117: 105403, 2021 12.
Article em En | MEDLINE | ID: mdl-34758434
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Amidoidrolases / Glicosídeos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Amidoidrolases / Glicosídeos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article