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Circulating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial.
Nakamura, Yoshiaki; Okamoto, Wataru; Kato, Takeshi; Esaki, Taito; Kato, Ken; Komatsu, Yoshito; Yuki, Satoshi; Masuishi, Toshiki; Nishina, Tomohiro; Ebi, Hiromichi; Sawada, Kentaro; Taniguchi, Hiroya; Fuse, Nozomu; Nomura, Shogo; Fukui, Makoto; Matsuda, Seiko; Sakamoto, Yasutoshi; Uchigata, Hiroshi; Kitajima, Kana; Kuramoto, Naomi; Asakawa, Takashi; Olsen, Steve; Odegaard, Justin I; Sato, Akihiro; Fujii, Satoshi; Ohtsu, Atsushi; Yoshino, Takayuki.
Afiliação
  • Nakamura Y; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Okamoto W; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Kato T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Esaki T; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Kato K; Cancer Treatment Center, Hiroshima University Hospital, Hiroshima, Japan.
  • Komatsu Y; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
  • Yuki S; Department of Gastrointestinal and Medical Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
  • Masuishi T; Department of Head and Neck, Esophageal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
  • Nishina T; Department of Cancer Center, Hokkaido University Hospital, Sapporo, Japan.
  • Ebi H; Department of Gastroenterology and Hepatology, Hokkaido University Hospital, Sapporo, Japan.
  • Sawada K; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Taniguchi H; Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
  • Fuse N; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, Japan.
  • Nomura S; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Fukui M; Department of Medical Oncology, Kushiro Rosai Hospital, Kushiro, Japan.
  • Matsuda S; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Sakamoto Y; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Uchigata H; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Kitajima K; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Japan.
  • Kuramoto N; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Japan.
  • Asakawa T; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Japan.
  • Olsen S; Clinical Research Support Office, National Cancer Center Hospital East, Kashiwa, Japan.
  • Odegaard JI; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Sato A; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Fujii S; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Ohtsu A; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.
  • Yoshino T; Chugai Pharmaceutical Co., Ltd, Tokyo, Japan.
Nat Med ; 27(11): 1899-1903, 2021 11.
Article em En | MEDLINE | ID: mdl-34764486
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Receptor ErbB-2 / Anticorpos Monoclonais Humanizados / Trastuzumab / DNA Tumoral Circulante / Antineoplásicos Imunológicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Receptor ErbB-2 / Anticorpos Monoclonais Humanizados / Trastuzumab / DNA Tumoral Circulante / Antineoplásicos Imunológicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article