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Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Liu, Fangbing; Zhao, Qiushi; Su, Yongwei; Lv, Jing; Gai, Yuqing; Liu, Shuang; Lin, Hai; Wang, Yue; Wang, Guan.
Afiliação
  • Liu F; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Zhao Q; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Su Y; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Lv J; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Gai Y; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Liu S; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Lin H; Department of Hematology and Oncology, First Hospital of Jilin University, Changchun, China.
  • Wang Y; Department of Pediatric Hematology and Oncology, First Hospital of Jilin University, Changchun, China. Electronic address: wang_yue@jlu.edu.cn.
  • Wang G; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, Ministry of Education, School of Life Sciences, Jilin University, Changchun, China;. Electronic address: wg10@jlu.edu.cn.
Exp Hematol ; 105: 39-49, 2022 01.
Article em En | MEDLINE | ID: mdl-34767916
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Tiofenos / Leucemia Mieloide Aguda / Resistencia a Medicamentos Antineoplásicos / Compostos Bicíclicos Heterocíclicos com Pontes / Citarabina / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Tiofenos / Leucemia Mieloide Aguda / Resistencia a Medicamentos Antineoplásicos / Compostos Bicíclicos Heterocíclicos com Pontes / Citarabina / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article