MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer.

Pan, Hongli; Pan, Zhenhua; Guo, Fengjie; Meng, Fanrong; Zu, Lingling; Fan, Yaguang; Li, Yang; Li, Mengjie; Du, Xinxin; Zhang, Xiuwen; Shao, Yi; Wei, Mingming; Li, Xuebing; Zhou, Qinghua

Pan, Hongli; Pan, Zhenhua; Guo, Fengjie; Meng, Fanrong; Zu, Lingling; Fan, Yaguang; Li, Yang; Li, Mengjie; Du, Xinxin; Zhang, Xiuwen; Shao, Yi; Wei, Mingming; Li, Xuebing; Zhou, Qinghua.

Afiliação

Pan H; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Pan Z; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Guo F; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Meng F; Tianjin Prenatal Diagnostic Center, Obstetrics and Gynecology Department, Tianjin Medical University General Hospital, Tianjin, China.
Zu L; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Fan Y; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Li Y; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Li M; Sichuan Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Du X; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China.
Zhang X; Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Shao Y; Department of Thoracic Surgery, Yizheng People's Hospital, Yangzhou, Jiangsu Province, China.
Wei M; Department of Oncology, Tianjin Medical University General Hospital, Tianjin, China.
Li X; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, China. mingmingshengwu@163.com.
Zhou Q; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China. xbli@tmu.edu.cn.

BMC Cancer ; 21(1): 1218, 2021 Nov 13.

Article em En | MEDLINE | ID: mdl-34774019

Assuntos

Carcinoma Pulmonar de Células não Pequenas/genética; Proteínas de Ligação a DNA/genética; Expressão Gênica; Chaperonas de Histonas/genética; Neoplasias Pulmonares/genética; MicroRNAs/fisiologia; Células A549; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Carcinoma Pulmonar de Células não Pequenas/mortalidade; Carcinoma Pulmonar de Células não Pequenas/patologia; Movimento Celular/genética; Proteínas de Ligação a DNA/antagonistas & inibidores; Proteínas de Ligação a DNA/metabolismo; Regulação para Baixo; Transição Epitelial-Mesenquimal/genética; Feminino; Genes Reporter; Genes Supressores de Tumor/fisiologia; Chaperonas de Histonas/antagonistas & inibidores; Chaperonas de Histonas/metabolismo; Humanos; Fator 4 Semelhante a Kruppel/genética; Fator 4 Semelhante a Kruppel/metabolismo; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/patologia; Masculino; Metiltransferases/genética; Metiltransferases/metabolismo; MicroRNAs/genética; Pessoa de Meia-Idade; Invasividade Neoplásica/genética; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo

Palavras-chave

Invasion; Migration; NSCLC; SET; miR-1915-3p

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Expressão Gênica / Carcinoma Pulmonar de Células não Pequenas / MicroRNAs / Proteínas de Ligação a DNA / Chaperonas de Histonas / Neoplasias Pulmonares Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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