A Meta-Analysis of the Risk Factors of Persistent Pulmonary Hypertension in Newborns.
Front Pediatr
; 9: 659137, 2021.
Article
em En
| MEDLINE
| ID: mdl-34778120
ABSTRACT
Objective:
To determine the risk factors of persistent pulmonary hypertension of the newborn using a meta-analysis method and provide a reference for its clinical prevention and treatment.Methods:
A meta-analysis was performed by searching the PubMed, Embase, Cochrane Library, China Biology Medicine Disc, Wanfang, and Chinese VIP journal databases, as well as the China National Knowledge Infrastructure.Results:
A total of 22 references were included in the meta-analysis; the cumulative medical records comprised 7,937 cases, and 2,613,072 control cases were included. A total of 12 related risk factors were included (7 were associated with pregnant women and 5 were associated with newborns).Conclusion:
Among the 12 associated risk factors included, the three most important and their combined odds ratio values and 95% CI were as follows (1) pregnant women smoking, 4.85 (1.98-11.9) during pregnancy; (2) gestational weeks <37, 4.34 (1.64-11.5); (3) perinatal asphyxia, 3.9 (2.87-5.31).
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
/
Systematic_reviews
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article