k-t accelerated multi-VENC 4D flow MRI improves vortex assessment in pulmonary hypertension.
Eur J Radiol
; 145: 110035, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34801875
ABSTRACT
BACKGROUND:
4D flow imaging can be used to evaluate vortex formation in the pulmonary artery seen in patients with pulmonary hypertension. We evaluated if a k-t accelerated multi-VENC (velocity encoding) 4D flow acquisition improves image quality, inter-reader agreement and correlation with hemodynamic parameters.METHODS:
A total of 14 patients with pulmonary hypertension (5 females, 9 males; mean age 61 ± 16 years) underwent 4D flow MRI (magnetic resonance imaging) and right heart catheterization. In addition to that, 13 healthy volunteers (2 females, 11 males, mean age 33 ± 12 years) also underwent 4D flow MRI. Multi- and single-VENC datasets were reconstructed and evaluated for vortex formation and vortex duration by two blinded readers and image quality was rated on a 5-point scale.RESULTS:
Both readers rated image quality as significantly higher on multi-VENC datasets (3.96 ± 0.71 vs. 2.56 ± 0.93, p < 0.001; 4.70 ± 0.61 vs. 4.07 ± 0.92, p = 0.003). Inter-reader correlation for vortex duration quantification was higher on multi-VENC datasets compared to single-VENC datasets (r = 0.63 vs. r = 0.44). No significant correlation was found between vortex duration and mean pulmonary artery pressure in patients with PH.CONCLUSION:
Multi-VENC 4D flow MRI significantly improves image quality and inter-reader agreement for the evaluation of vortex formation in the pulmonary artery.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hipertensão Pulmonar
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article