The log odds of positive neck lymph nodes is a superior lymph node predictor for overall survival in head and neck cancer: a population-based analysis in Germany.
Eur Arch Otorhinolaryngol
; 279(7): 3587-3595, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-34807283
ABSTRACT
BACKGROUND:
This population-based study investigated the influence of different lymph node (LN) classifications on overall survival (OS) in head and neck cancer (HNC).METHODS:
401 patients (median age 57 years; 47% stage IV) of the Thuringian cancer registries with diagnosis of a primary HNC receiving a neck dissection (ND) in 2009 and 2010 were included. OS was assessed in relation to total number of LN removed, number of positive LN, LN ratio, and log odds of positive LN (LODDS).RESULTS:
Mean number of LODDS was 0-0.96 ± 0.57. When limiting the multivariate analysis to TNM stage, only the UICC staging (stage IV HR 9.218; 95% CI 2.721-31.224; p < 0.001) and LODDS > - 1.0 (HR 2.120; 95% CI 1.129-3.982; p = 0.019) were independently associated with lower OS.CONCLUSION:
LODDS was an independent and superior predictor for OS in HNC in a population-based setting with representative real-life data.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias de Cabeça e Pescoço
/
Linfonodos
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article