Unsupervised hyperspectral stimulated Raman microscopy image enhancement: denoising and segmentation via one-shot deep learning.
Opt Express
; 29(21): 34205-34219, 2021 Oct 11.
Article
em En
| MEDLINE
| ID: mdl-34809216
ABSTRACT
Hyperspectral stimulated Raman scattering (SRS) microscopy is a label-free technique for biomedical and mineralogical imaging which can suffer from low signal-to-noise ratios. Here we demonstrate the use of an unsupervised deep learning neural network for rapid and automatic denoising of SRS images UHRED (Unsupervised Hyperspectral Resolution Enhancement and Denoising). UHRED is capable of "one-shot" learning; only one hyperspectral image is needed, with no requirements for training on previously labelled datasets or images. Furthermore, by applying a k-means clustering algorithm to the processed data, we demonstrate automatic, unsupervised image segmentation, yielding, without prior knowledge of the sample, intuitive chemical species maps, as shown here for a lithium ore sample.
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MEDLINE
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En
Ano de publicação:
2021
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Article