Prediction of the CYP2D6 enzymatic activity based on investigating of the CYP2D6 genotypes around the vivax malaria patients in Yunnan Province, China.

Dong, Ying; Huang, Herong; Deng, Yan; Xu, Yanchun; Chen, Mengni; Liu, Yan; Zhang, Canglin

Dong, Ying; Huang, Herong; Deng, Yan; Xu, Yanchun; Chen, Mengni; Liu, Yan; Zhang, Canglin.

Afiliação

Dong Y; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China. luxidongying@126.com.
Huang H; Department of Basic Medical Sciences, Clinical College of Anhui Medical University, Hefei, 230031, China.
Deng Y; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China.
Xu Y; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China.
Chen M; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China.
Liu Y; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China.
Zhang C; Yunnan Institute of Parasitic Diseases Control, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Centre of Malaria Research, Pu'er, 665000, China.

Malar J ; 20(1): 448, 2021 Nov 25.

Article em En | MEDLINE | ID: mdl-34823523

Assuntos

Citocromo P-450 CYP2D6/metabolismo; Genótipo; Malária Vivax/parasitologia; Plasmodium vivax/fisiologia; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Criança; Pré-Escolar; China; Feminino; Humanos; Lactente; Recém-Nascido; Masculino; Pessoa de Meia-Idade; Adulto Jovem

Palavras-chave

CYP2D6; Enzyme activity; Genotype; Prediction; Vivax malaria patient; Yunnan Province

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium vivax / Malária Vivax / Citocromo P-450 CYP2D6 / Genótipo Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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